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Grants and contracts awarded to Yale School of Medicine, July/August 2005
Federal
- Serap Aksoy, NIH, Trypanosome Gene Expression in Tsetse,
2 years, $163,500
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Robert Alpern, NIH, Regulation of Renal
Bicarbonate and Chloride Absorption, 5 years, $2,043,750
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Roland
Baron, NIH, Role of the c-SRS Proto-Oncogene
in Osteoblasts, 5 years, $1,798,500
- Sumita Bhaduri-McIntosh,
NIH, Early Cellular Immune Responses to EBV, 4 years,
$535,680
- Angelique Bordey, NIH, GABA Signaling
in the Postnatal Subventricular Zone, 4 years, $1,483,007
-
Robert Camp, NIH, Qualitative Analysis of Tissue Biomarkers
and Pathways, 2 years, $281,220
- Michael Caplan, NIH, Ion Pump Partners: Regulators
of Sorting and Function, 4 years, $1,702,179
- Sonia Caprio, NIH, Pathophysiology of Type
2 Diabetes in Youth, 5 years, $2,043,750
- R. Todd Constable, NIH, Epileptogenic Tissue
Localization Using EEG-fMRI, 4 years, $1,500,511
- Joseph Craft, NIH, Immune Responses in Lupus,
5 years, $1,635,000
- Ralph DiLeone, NIH, Role of the Orexin Neuropeptide
in Responses to Morphine, 5 years, $1,455,000
- Daniel DiMaio, NIH, Cell Transformation
by Bovine Papillomavirus, 5 years, $2,630,896
- Ronald Duman, NIH, Antidepressants and Signal
Transduction and Gene Expression, 5 years, $1,818,750
- Jack Elias, NIH, Protease/Cathepsin-Mediated
Apoptosis in COPD, 4 years, $1,635,000
- Jorge Galan, NIH, Molecular Genetic Analysis
of Salmonella Cell Invasion, 1 year, $2,343,717
- Joel Gelernter, NIH, Genetics of Opioid
Dependence, 5 years, $5,779,192
- Sankar Ghosh, NIH, Subversion of Innate
Immune Responses by Brucella, 2 years, $433,750
- Thomas Gill, NIH, Epidemiology of Disability
and Recovery in Older Persons, 5 years, $3,152,866
- Daniel Goldstein, NIH, Strategies to Enhance
Immunity in Aging, 3 years, $648,000
- Carlos Grilo, NIH, Patient-Oriented Research
with a Focus on Eating and Weight Disorders, 5 years, $597,160
- Steven Hebert, NIH, Structure and Function
of ROMK Channel in Kidney, 4 years, $1,370,692
- Zeev Kain, NIH, Parent/Health Care Provider
Behaviors & Child’s
Anxiety, 5 years, $2,659,446
- Harlan Krumholz, NIH, Telemonitoring to
Improve Heart Failure Outcomes, 4 years, $6,664,663
- Nian Liu, NIH, Content-Based Indexing and
Retrieval of Brain Odor Maps, 3 years, $470,339
- Angeliki Louvi, NIH, Development of Choroid
Plexus and the Blood-CSF Barrier, 2 years, $395,933
- Shrikant Mane, NIH, Yale Microarray Center
for Research on the Nervous System, 5 years, $6,509,106
- Linda
Mayes, NIH, Cortical Maturation and
ERPS in Cocaine-Exposed Children, 5 years, $631,800
- Diane McMahon-Pratt, NIH, Intervenable Host
Leishmania (Viannia) Interactions, 5 years, $5,166,089
- Thomas Morgan, NIH, Genetic Risk Factors
for Myocardial Infarction, 5 years, $846,072
- A. David Paltiel, NIH, Evaluating the Link
Between HIV Prevention and Treatment, 3 years, $1,487,112
- Jordan Pober, NIH, Human CTL-Mediated Injury
of Graft Endothelial Cells, 5 years, $2,177,410
- Marc Potenza, NIH, fMRI of Craving in Addictions:
Gender Differences, 5 years, $1,604,920
- Kenneth Pugh, NIH, Neurobiological Foundations
in Reading (Dis)Ability, 5 years, $2,970,826
- Timothy Quan,
NIH, The Role of Epstein-Barr Virus in Systemic Lupus Erythematosus,
5 years, $613,967
- Gary Rudnick, NIH, Structure and Function
of NSS Transporters, 4 years, $1,238,981
- Charles Sanislow,
NIH, Cognitive Control in Borderline & Trauma
Psychopathology, 5 years, $887,895
- William Sessa,
NIH, Regulation of Vascular Remodeling & Angiogenesis
by Nogo, 5 years, $2,043,750
- Nenad Sestan, NIH,
Molecular Control of Cortical Neural Stem Cells, 5 years, $1,717,912;
NIH, Neurobiology of Speech and Language Development, 4 years,
$1,512,376
- Albert Shaw, NIH, Top3 Homologues in Lymphocyte
Genome Stability and Aging, 5 years, $1,417,925
- Dieter Söll, NSF, Expanding the Genetic
Code with Phosphoserine and Pyrrolysine, 1 year, $171,569
- Stephen Strittmatter, NIH, Axonal Growth
Cone Signal Transduction, 4 years, $1,512,376
- Zhaoxia Sun, NIH, SCO, a Zebrafish Model,
Links Cilia and Kidney Cysts, 5 years, $1,921,125
- Patrick Sung, NIH, DNA Repair Genes & Proteins
of the RAD52 Group, 5 years, $1,941,565
- Edwin Thrower,
NIH, Pancreatic Zymogen Activation in a Reconstituted System,
2 years, $260,800
- Helen Treloar, NIH, Development of the Primary
Olfactory Pathway, 5 years, $1,430,625
- Marietta Vazquez, NIH, Epidemiology of Human
Metapneumovirus Infection, 5 years, $676,986
- Marney White, NIH, Craving, Binge Eating,
and Obesity, 5 years, $671,571
- John Wysolmerski, NIH, Function of the Calcium-Sensing
Receptor in the Breast, 5 years, $1,675,875
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With support from the G. Harold and Leila Y. Mathers Charitable Foundation, Professor of Cell Biology Pietro De Camilli studies synaptic vesicles. In this micrograph of rat hippocampus, an enzyme involved in the synthesis of PIP2, a lipid that is crucial to vesicle formation, is labeled in green.
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Non-Federal
- Patrick Allen, National Alliance for Research on Schizophrenia
and Depression, Analysis of Protein Phosphatase-Mediated Glutamate Receptor
Regulation, 2 years, $60,000
- George Anderson, University of Pittsburgh, Neurobiology,
Impulsivity and Alcoholism, 4 years, $45,404
- Titus Boggon, American Society of Hematology, Structure/Function
Studies of Janus Kinase Family Members, 1 year, $50,000
- Alfred Bothwell, Robert Leet and Clara Guthrie Patterson
Trust, Bioengineering Functional Islets for Treatment of Type 1 Diabetes,
1 year, $59,999
- H. Kim Bottomly, Mount Sinai School of Medicine, Immunobiology
of Peanut Allergy and Its Treatment: A Prototype, 5 years, $239,654
- Demetrios Braddock, American Cancer Society, Inc., Molecular
Determinants of Nucleic Acid Recognition by KH Domains, 2 years, $720,000
- Christopher Breuer, American Surgical Association, Investigating
the Growth Potential of Tissue-Engineered Venous Conduits in a Juvenile Lamb
Model, 2 years, $75,000
- Darlene Brunzell, National Alliance for Research on Schizophrenia
and Depression, Beta2 Nicotinic Acetylcholine Receptors Affect Schizophrenia
Phenotypes via Modulation of CREB, 2 years, $59,968
- João Cabral, American Heart Association (Heritage Affiliate), Biophysical
Studies of a Bacterial Cyclic Nucleotide-Regulated Channel, 3 years,
$198,000
- Cecilia Canessa, American Heart Association (Heritage
Affiliate), Functional Analysis of SGK1 in Vivo, 3 years, $198,000
- Daniel Chase, National Parkinson Foundation, Inc., Identification
of the Molecular Mechanisms of Dopamine Signaling, 1 year, $40,000
- Yung-Chi Cheng, Kagoshima University, Novel Nucleoside
Reverse Transcriptase Inhibitors Active Against Multi-Drug Resistance HIC-1,
1 year, $35,736
- Hongbo Chi, Arthritis National Research Foundation, SIPI-Mediated
Regulation of Autoimmune Disease, 1 year, $50,000
- Chuhan Chung, American Liver Foundation, Hepatocellular
Carcinoma and Hepatic Stellate Cells Express Antiangiogenic Pigment Epithelium-Derived
Factor; Epigenetic Regulation of PEDF Occurs Through DDR2 Activation on HSC,
3 years, $225,000
- David Cone, National Academies of Emergency Dispatch, Can
EMD Conserve Scarce EMS Resources?, 1 year, $3,500
- Vladimir Coric, National Alliance for Research on Schizophrenia
and Depression, Endocannabinoid Receptor Modulation and Obsessive-Compulsive
Disorder: A Double Blind, Placebo-Controlled Pilot Study of Dronabinol Addition
in Serotonin-Reuptake Inhibitor-Resistant OCD, 2 years, $59,760
- Kristina Crothers, American Lung Association, Chronic
Obstructive Pulmonary Disease in HIV-Positive Compared to HIV-Negative Patients,
1 year, $40,000
- Madison Cuffy, The Thoracic Surgery Foundation for Research
and Education, The Role of Indoleamine 2,3-Diosygenase (IDO) on Modulation
of Immune Responses in Inflammatory Arterial Diseases, 2 years, $50,000
- Jan Czyzyk, American Cancer Society, Inc., Alternative
Effectors of Ras GTPase in T Cell Activation, 4 years, $720,000
- Pietro De Camilli, G. Harold and Leila Y. Mathers Charitable
Foundation, Molecular Mechanisms of Synaptic Vesicle Biogenesis,
3 years, $1,650,179
- Marie Egan, Cystic Fibrosis Foundation, Cystic Fibrosis
Center, 1 year, $55,310
- Barbara Ehrlich, American Society of Nephrology, Regulation
and Function of Polycystin-2, 1 year, $50,000
- Richard Flavell, Bill and Melinda Gates Foundation, A
Mouse Model to Evaluate Live Attenuated Vaccine Candidates, 5 years,
$16,968,506; Alzheimer’s Association, An Inducible Mouse to Elucidate
the Role of Immunity/Inflammation in AD, 3 years, $234,498
- Gerald Friedland, Virginia Commonwealth University, Opioids
and HIV Medications: Interactions in Drug Users, 1 year, $37,632
- Mark Gerstein, Rutgers University, Structural Genomics
of Eukaryotic Domain Families, 5 years, $230,041
- Daniel Goldstein, American Society of Transplantation, Role
of the Innate Immune Ligand Heat Shock Protein 70 in Transplantation,
2 years, $80,000
- Jonathan Grauer, Medtronic, Inc., New Zealand White
Rabbit Pseudarthrosis Study Evaluating INFUSE and CRM Products, 1 year,
$210,138
- Handan Gunduz-Bruce, National Alliance for Research on
Schizophrenia and Depression, GABA-Glutamate Interactions and Psychosis,
2 years, $30,000
- Ann Haberman, The S.L.E. Foundation, Inc., How Germinal
Centers Select High-Affinity B Cells: Determination of Cellular Interactions
and Migratory Behavior via Intravital Microscopy, 3 years, $150,000
- Ala Haddadin, Union Mutual Foundation, High-Dose
Statin Therapy in the Preoperative Period, 2 years, $25,000
- Bryan Hains, Pfizer, Inc., Pifzer Scholars in Pain
Medicine, 2 years, $123,000
- Martha Harding, AGA Foundation for Digestive Health and
Nutrition, Hepatitis C Virus Infection of Human Liver-Chimeric Mice,
3 years, $195,000
- Lise Heginbotham, American Heart Association (Heritage
Affiliate), Regulation of Ca2+ Transport Proteins, 3 years, $198,000
- Josephine Hoh, The Ellison Medical Foundation, Trans-Racial
Gene Mapping for Age-Related Macular Degeneration, 4 years, $200,000
- Akiko Iwasaki, Burroughs Wellcome Fund, Stromal Cell
Contributions in Innate and Adaptive Immune Response to Mucosal Viral Infection,
5 years, $400,000
- Jeffrey Kahn, American Heart Association (Heritage Affiliate), The
Role of a Novel Human Coronavirus in Kawasaki Disease, 3 years, $198,000
- Insoo Kang, American Foundation for AIDS Research, The
Effect of Aging on IL-7 Mediated CD8+ T Cell Survival, 2 years, $60,000
- Anil Karihaloo, National Kidney Foundation, VEGF
Signaling in Renal Tubular Epithelia, 1 year, $100,000
- Stuart Katz, American Heart Association, Erythropoietin
in Acute Myocardial Infarction, 1 year, $66,000
- Barbara Kazmierczak, L2 Diagnostics, LLC, Virulence
Typing of Pseudomonas Clinical Isolates, 1 year, $158,204
- Judith Kidd, University of Florida, Taste Psychophysics,
1 year, $76,779
- Fadi Lakkis, American Society of Nephrology, Model
Organism to Study Innate Allorecognition, 1 year, $50,000
- Angelika Lampert, Epilepsy Foundation of America, Control
of Excitability in Rodent Spike-Wave Seizures by Voltage-Gated Sodium Channels,
1 year, $40,000
- Brian Leaderer, Brigham and Women’s Hospital, Gene
by Environment Interactions in Asthma and Allergy, 1 year, $185,331
- Patty Lee, American Lung Association, MIMED Mechanisms
of VEGF and HO-1, 1 year, $60,000
- Xin Li, Arthritis Foundation, Role of Borrellia burgdoferi NapA
in Lyme Arthritis, 2 years, $150,000
- Yi-Hwa Liu, American Heart Association (Heritage Affiliate), Development
of Quantitative High Resolution and High Sensitivity for Targeted Molecular
Imaging, 3 years, $198,000
- Elias Lolis, The Campbell Foundation, CXCR4 Allosteric
Agonists, 1 year, $11,603
- Gero Miesenböck, The Dana Foundation, Illuminating
the Function of Hypothalamic Feeding Circuits, 3 years, $300,000
- Angus Nairn, Rockefeller University, Molecular Actions
of Neuroleptic Drugs, 1 year, $288,288
- Michael Nitabach, Whitehall Foundation, Inc., Clock-Membrane
Coupling in Circadian Pacemaker Neurons, 1 year, $75,000
- Aldo Peixoto, Satellite Research, Hemodynamic and
Hormonal Response to Dialysate Sodium Individualization in Hemodialysis Patients,
1 year, $50,000
- Patricia Preisig, University of Texas Southwestern Medical
Center at Dallas, The Formulation of a Rational Therapy of Nephrolithiasis,
3 years, $123,703
- Timothy Quan, Arthritis Foundation, The Role of Epstein-Barr
Virus in Systemic Lupus Erythematosus, 2 years, $150,000; Abbott Laboratories,
Inc., The Role of Epstein-Barr Virus in Systemic Lupus Erythematosus,
1 year, $72,000
- Gary Rudnick, National Alliance for Autism Research, Mutation
Associated with Asperger’s Syndrome—Effect on Amine Transporter System,
2 years, $120,275
- Raymond Russell, Dr. Robert C. Atkins Foundation, Effects
of a High-Protein Ketogenic Diet on Myocardial Metabolism, 1 year, $91,615
- Kristi Sacco, National Alliance for Research on Schizophrenia
and Depression, Effects of Atomoxetine on Cognitive Function in Schizophrenia,
2 years, $60,000
- Mary Schwab-Stone, Fundación Quiera, Quiera-Yale
Children of the Street, 1 year, $10,211
- Gerald Shadel, A-T Childrens’ Project, Aberrant Regulation
of Mitochondrial DNA in Ataxia-Telangiectasia, 2 years, $42,263
- Arthur Simen, National Alliance for Research on Schizophrenia
and Depression, Quantitative Trait Mapping in a Large Mormon Pedigree
with Severe Depression and Anxiety, 2 years, $60,000
- Albert Sinusas, GE Healthcare Ltd., Evaluation of
Ventricular Remodeling in Animals Using SPECT Imaging After Myocardial Infarction,
7 months, amount confidential
- William Sledge, Eli Lilly and Company, YNHH Recidivist
Program Prevention Evaluation with Six Sigma Methodology, 1 year, $129,553
- Stefan Somlo, The Joseph LeRoy and Ann C. Warner Fund,
Inc., ARPKD Research, 1 year, $25,000
- Julie Sosa, Patrick and Catherine Weldon Donaghue Medical
Research Foundation, Neurocognitive Changes in Primary Hyperparathyroidism,
3 years, $179,374
- Julie Staley-Gottschalk, National Alliance for Research
on Schizophrenia and Depression, Antidepressant-Mediated Adaptations in
Nicotinic Acetylcholine Receptor Expression, 2 years, $60,000
- Mary Tomayko, Dermatology Foundation, Phenotypic
and Functional Analysis of Memory B cells, 3 years, $165,000
- Flora Vaccarino, National Alliance for Autism Research, Molecular
Mechanisms of Cerebral Cortical Overgrowth, 2 years, $119,276
- Lisa Walke, American Geriatrics Society, Barriers
to and Facilitators of Effective Symptom Management in Older Adults with
Chronic Obstructive Pulmonary Disease, 2 years, $130,000
- Li Wen, American Diabetes Association, Inc., The
Role of Toll in Autoimmune Diabetes, 3 years, $300,000
- Kevin White, University of California–Riverside, Molecular
Bases of Ecdysteroid Action in the Mosquito, 5 years, $157,982
- Catherine Yeckel, American Diabetes Association, Inc., Mild
Cold Exposure: A Non-Pharmacological Approach to Improve Insulin Sensitivity
In Obese Youth, 3 years, $414,000
- Mark Yeckel, National Parkinson Foundation, Inc., Dopaminergic
and Cholinergic Control of Inhibitory Connectivity Between Direct and Indirect
Output Pathways of the Neostriatum Background, 1 year, $40,000
- Jiasheng Zhang, American Society of Nuclear Cardiology, Imaging
of Matrix Metalloproteinase Activity in Thoracic Aortic Aneurysm: A Pilot
Study, 1 year, $25,000
CORRECTION: The listing in Volume 1, Issue 3 for Brian Leaderer’s 5-year
NIH grant, Indoor and Outdoor NO2 and Asthma Severity in Children,
was incorrect. The correct grant amount is $6,544,369, for 5 years.
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