Medicine@Yale publication

Medicine@Yale.

January/February 2007   Volume 3 Issue 1

Inside this issue

Cover stories

Following in his father’s footsteps

$3 billion Yale campaign will benefit science and medicine

New genes found in Crohn’s disease, serious eye ailment

Partnerships

State makes first stem-cell grants to Yale

Grants & contracts

People

Lifelines: Joseph Schlessinger

Pediatric researcher is new ambassador for global health

Biologist cited for structural insights into action of antibiotics

Expert on blood pressure is honored

Education innovator wins award for work on transforming schools

Out & about

Awards & honors

Health

A robot arrives in the operating room

Science

A crystal-clear look at a puzzling protein

Magnetic resonance system will open new scientific vistas

Advances: In bacteria vs. worm, children are winners | Ruling fate of cellular blank slate | How the stressed become the depressed | The immune system in a sticky situation



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Grants and Contracts Awarded to Yale School of Medicine, May/June 2006

Federal

  • Morris Bell, NIH, Cognitive Training and Enhanced Supported Employment, 5 years, $2,138,756
  • Christopher Breuer, NIH, Development of Second-Generation Tissue-Engineered Vascular Grafts, 5 years, $673,650
  • Tania Burgert, NIH, Postprandial Glycemia in Association with Vascular Disease in Childhood Obesity, 3 years, $384,544
  • Elizabeth Claus, NIH, Meningioma: Risk Factors and Quality of Life, 5 years, $3,383,676
  • Mark Cullen, NIH, Disease, Disability and Death in an Aging Workforce, 5 years, $5,236,618
  • Pietro De Camilli, NIH, Molecular Mechanisms in Synaptic Vesicle Recycling, 4 years, $1,177,200
  • Robin de Graaf, NIH, Novel Technologies for Global Optimization of Magnetic Field Homogeneity, 2 years, $332,273
  • Enrique De La Cruz, NSF, Kinetic Mechanism of DEAD-box RNA Helicase ATPase, 5 years, $942,639
  • Donald Engelman, NIH, TM Interactions in Membrane Protein Folding and Function, 4 years, $1,754,952
  • Durland Fish, NIH, Spread of Lyme Borreliosis Bacteria in the U.S., 2 years, $449,625
  • Sankar Ghosh, NIH, Regulation and NF-κB and IκB Proteins, 5 years, $2,065,833
  • Erol Gulcicek, NIH, Differential Gel Electrophoresis (DIGE) System for Yale University Keck Laboratory, 1 year, $405,284
  • Joan Kaufman, NIH, Genetic and Environment Modifiers of Child Depression, 5 years, $1,858,595
  • Brian Leaderer, NIH, Asthma Severity in Children and Fine Particle Composition, 5 years, $2,819,762
  • Elias Lolis, NIH, Functional and Structural Studies of CD74 Activation, 5 years, $2,065,833
  • Xingguang Luo, NIH, Fine-Mapping the Risk Loci for Alcoholism in ADH Gene Cluster and ALDH2 Gene, 5 years, $732,816
  • Robert Malison, NIH, Drug Abuse, Sleep and Cognition, 3 years, $975,109
  • Ruslan Medzhitov, NIH, Cell Biology of TLR Signal Transduction, 5 years, $1,839,375
  • Gero Miesenboeck, Office of Naval Research, Computation in Neuronal Microcircuits, 1 year, $400,000
  • Michael Nathanson, NIH, Regulation of Liver by Nuclear Ca2+ Signaling, 5 years, $5,954,074
  • Jullie Pan, NIH, Metabolic Neuroprotection: Creative Supplementation in Human Brain, 2 years, $518,936
  • Nancy Ruddle, NIH, Lymphotoxin and Lymphoid Neogenesis, 1 year, $82,437
  • Albert Sinusas, NIH, Hybrid Imaging of Angiogenesis and Arteriogenesis, 4 years, $1,652,083
  • Anthony Van den Pol, NIH, Cytomegalovirus in the Brain, 5 years, $2,043,750
  • Detlef Wencker, NIH, Studies of Myocyte Apoptosis in Congestive Heart Failure, 5 years, $790,862
  • Sandra Wolin, NIH, Biogenesis of Small RNAs, 4 years, $1,346,148
  • Tongzhang Zheng, NIH, Environment, Gene and Testicular Cancer Risk, 5 years, $5,079,796

Non-Federal

  • Elizabeth Claus, Susan G. Komen Breast Cancer Foundation, Ductal Carcinoma in situ and BRCA1/2: Outcomes and Risk Prediction, 2 years, $249,823
  • Robert Constable, Pfizer, Inc., MR Methodologies and Further Analysis and Reporting of Data, 2 months, $25,181
  • Gail D’Onofrio, Yale-New Haven Health System, Disaster Preparedness and Emergency Response Education and Research, 1 year, $55,000
  • Deepak D’Souza, Astra Zeneca, L.P., Nicotinic Modulation of a Noncompetitive NMethyl-d-Aspartate (NMDA) Receptor Antagonist–Induced Schizophrenia-Like Information Processing Deficits in Humans, 1 year, $496,454
  • Daniel Goldstein, Roche Organ Transplantation Foundation, Role of Innate B1 Lymphocytes in Neonatal Transplant Tolerance, 2 years, $162,920
  • Zhiwei Hu, Susan G. Komen Breast Cancer Foundation, Targeting the Neovasculature for Immunotherapy and Photodynamic Therapy of Breast Cancer, 2 years, $250,000
  • Sven-Eric Jordt, Health Effects Institute, Health Effects of Air Pollution, 1 year, $80,000
  • Amy Justice, University of Kentucky, Computer Alcohol Interventions for HIV+ Veterans, 1 year, $29,219
  • Arie Kaffman, American Psychiatric Institute for Research and Education, The Effects of Postnatal Maternal Care on Neurogenesis During Development and Their Implications for the Development of Vulnerability to Stress, 1 year, $45,000
  • John Krystal, National Alliance for Research on Schizophrenia and Depression, GABRA2 Modulation of NMDA Receptor Deficit–Related PFC Dysfunction, 1 year, $100,000
  • Elias Lolis, University of Florida, Viral-Based Chemokine Receptor Antagonist, 1 year, $85,515; Avigen, Inc., Stage 1: Preliminary Characterization of a MIF Inhibitor, 1 year, $25,501
  • Paul Lombroso, National Alliance for Research on Schizophrenia and Depression, Characterization of the Step Knock-Out Mouse, 1 year, $99,360
  • Diane McMahon-Pratt, University of Iowa, Collaborative Development of a Vaccine Against Cutaneous and Visceral Leishmanias, 5 years, $156,176
  • Guillermo Mor, Novogen Limited, Assay of Induction Apoptosis by Phenoxodiol in Cancer Cells, 1 year, $89,920
  • Prakash Nadkarni, Mount Sinai School of Medicine, WTC Medical Monitoring Program Data and Preventive Medicine, 3 years, $506,698
  • Angus Nairn, National Alliance for Research on Schizophrenia and Depression, Neuroproteomic Analysis of the Actions of BDNF and Other Neurotrophic Factors, 1 year, $99,900
  • Jill Reiter, Susan G. Komen Breast Cancer Foundation, Prognostic Significance of Soluble EGFR Expression in Breast Cancer, 2 years, $250,000
  • Sara Rockwell, PharmaMar USA, Inc., Preliminary Studies of the Effects of Aplidine in Hypoxic Environments and in Combination with Radiation, 1 year, $67,035
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Copyright 2006, Yale University School of Medicine. All rights reserved. Email comments or suggestions to: editor@info.med.yale.edu