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Grants and contracts awarded to Yale School of Medicine
September/October 2006
Federal
With support from the National Institutes of Health, Matthew
State, M.D., PH.D., Harris Associate Professor of Child Psychiatry in the Child
Study Center, is studying the role of a gene known as SLITRK1 (bright blue areas
at top of photo) in Tourette’s syndrome and related disorders.
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- Maria Teresa Baquero, Department of the Army, Microtubule-Associated
Protein Expression and Predicting Taxane Response, 3 years, $96,120
- Clifford Bogue, NIH, Hex—A Homeobox Gene
Essential for Liver Development, 2 years, $432,300
- Lloyd Cantley, NIH, Stem Cells in Organ Maintenance
and Repair, 1 year, $12,000
- Thomas Carpenter, NIH, Center of Research Translation
Program (CORT), 5 years, $8,213,600
- Kathleen Carroll, NIH, Computer-Based Training
for Cognitive Behavioral Therapy, 3.5 years, $1,407,143
- Junjie Chen, NIH, Study of the Role of DNA Damage
Reponses in Tumorigenesis and Senescence, 4.5 years, $1,265,587; NIH, Analysis
of BRCA1 Function in DNA Repair, 4.5 years, $1,334,551; Department of Defense,
Genomic Instability and Breast Cancer, 4 years, $825,000
- Yung-Chi Cheng, NIH, Nucleoside Analogs as Anticancer
Compounds, 4.5 years, $1,495,498
- Judy Cho, NIH, Mapping Chromosome 3q Inflammatory
Bowel Disease, 3 years, $867,270
- Jimmy Choi, NIH, Motivation and Learning in Schizophrenia,
1 year, $56,199
- Vladimir Coric, National Geospatial-Intelligence Agency,
Efficacy of Forensic Analysis in Detecting Deception During High Stress
Situations, 1 year, $119,632
- Kelly Cosgrove, NIH, Brain Imaging of Sex Differences
in Tobacco Smokers, 5 years, $893,700
- Joseph Craft, NIH, Genetic Analysis of T Cells
in Lupus, 5 years, $1,818,504
- Alan Dardik, NIH, Flow Responses to Carotid Angioplasty,
4.5 years, $665,550
- Christopher DeFeo, NIH, Structure and Function
of the Human Copper Transporter, 2 years, $66,060
- James Duncan, NIH, LV Strain Quantification from
4D Echocardiography, 4.5 years, $7,244,829
- Brian Elbel, Agency for Health Care Research and Quality,
Choice Sets and Consumer Selection of Health Plans,1 year, $32,400
- Julia Etchin, Department of the Army, Molecular
Basis for BRCA2-Mediated DNA Repair and Breast Tumor Supression, 3 years,
$97,200
- Leigh Evans, Agency for Health Care Research and Quality,
Simulation Training for Ultrasound Guided Central Venous Catheter Insertion,
2 years, $532,681
- John Forrest, NIH, Yale Predoctoral Clinical Research
Training Program, 1 month, $581,683
- Jorge Galán, NIH, Predoctoral Training
Program in Microbial Pathogenesis, 5 years, $1,061,569
- Joel Gelernter, NIH, Genetics of Cocaine Dependence,
4 years, 7 months, $5,980,328
- Harindarpal Gill, NIH, NBCe1 and n1: Crystal Structure
Determination, 2 years, $85,989
- Charles Greer, NIH, Mechanisms of Aging in the
Olfactory System,5 years, $6,652,339
- Mridu Gulati, National Institute for Occupational
Safety and Health, Longitudinal Study of Respiratory Function in Aluminum
Smelter Workers, 3 years, $291,600
- Noam Harel, NIH, Nogo’s Role in Intracellular
Trafficking, 4.5 years, $782,316
- George Heninger, NIH, Substance Abuse Education
for Medical Students, 2.5 years, $652,532; NIH, Clinical and Basic
Neurobiology of Nervous System Diseases, 2 years, $134,362
- Henry Huang, NIH, New PET Radioligand for Serotonin
Transporter, 2 years, $714,183
- Karl Insogna, NIH, Impact of a Protein Supplement
on Bone Mass in Older Women, 4 years, $1,876,418
- Sven-Eric Jordt, NIH, TRPA1 Channels in Sensory
Neurons as Targets for Environmental Irritants, 5 years, $2,390,822; NIH,
Sensory Neural Mechanisms of Pulmonary Agent and Vesicant Toxicity,
4.5 years, $2,446,733
- Amy Justice, NIH, Veterans Aging Cohort Study,
5 years, $13,928,272
- Joan Kaufman, NIH, Genetic and Environment Modifiers
of Child Depression, 4.5 years, $1,858,595
- Trace Kershaw, NIH, HIV/STD Risk Among Young Expectant
Fathers: Relationship Attachment and Transition, 4.5 years, $2,537,672
- Michael Krauthammer, NIH, Text Mining as a Translational
Tool in Biomedicine, 3 years, $439,857
- Daeyeol Lee, NIH, Cortical Mechanisms of Sequence
Learning, 7 months, $303,729
- Chiang-Shan Li, NIH, Imaging Inhibitory Control
in Cocaine Dependence, 1 year, $208,800
- Haifan Lin, NIH, Regulation of Germline Stem Cell
Division in Drosophila, 1 year, $94,875
- Brett Lindenbach, NIH, Hepatocellular Carcinoma:
Targeting HVC Replication, 3.5 years, $613,302
- Xiaomei Ma, NIH, Myelodysplastic Syndromes: Previous
Exposures, Survival, and Quality of Life, 5 years, $698,600
- Robert Malison, NIH, Genetics of Opioid Dependence
in a Hmong (Thai) Isolate, 2 years, $553,320
- Irvin Modlin, NIH, Molecular Strategies to Define
Carcinoids and Rationalize Surgical Intervention, 3.5 years, $1,173,350
- Laura Niklason, NIH, Biological Vascular Grafts,
4 years, 7 months, $3,477,864
- Jordan Pober, NIH, Chronic DTH and IFN-gamma in
Human Graft Arteriosclerosis, 5 years, $11,635,495
- Vazhaikkurichi Rajendran, NIH, Role of IK Channels
in Rat Distal Colon, 5 months, $1,614
- Faye Rogers, NIH, Altered Helical Structures:
Repair and Induction of Genomic Instability, 3 years, $445,161
- Robert Sherwin, NIH, Clinical and Translational
Science Award TL1, 4.5 years, $57,330,994
- Arthur Simen, NIH, Epigenetic Factors in Stress-Enhanced
Acquisition of Cocaine Self-Administration, 2 years, $330,083
- Dennis Spencer, NIH, Origin of Extracellular Glutamate
in Human Temporal Lobe Epilepsy, 3.5 years, $2,056,128
- Matthew State, NIH, The Role of SLITRK1 in Tourette
and Related Disorders, 5 years, $2,217,291
- Rebecca Sweet, NIH, Autoimmune Memory Development
and Maintenance, 2.5 years, $127,392
- Fred Volkmar, NIH, Autism and Related Disorders:
Development and Outcome, 5 years, $5,906,778
- Kathleen Wilson, Department of the Army, The Roles
of NFBD1, 53BP1, and BRCA1 in the DNA Damage Response, 3 years, $96,746
- Dianqing Wu, NIH, Wnt Signaling and Bone Biology,
3 years, 6 months, $1,521,756; NIH, Molecular Function of Chemoattractant-Mediated
Signaling, 3 years, 6 months, $1,776,906
Non-Federal
- Ali Abu-Alfa, Genzyme, Genzyme–Yale Educational
Conferences, 7 months, $20,700
- Diana Beardsley, University of Massachusetts, Prevention
of the Complications of Bleeding Disorders, 1 year, $23,189
- Henry Binder, Christian Medical College Hospital,
Comprehensive Studies of a New Improved Oral Rehydration Solution for Diarrheal
Disease, 1 year, $69,250
- Hilary Blumberg, National Alliance for Research on
Schizophrenia and Depression, Frontal Markers of Vulnerability and Resilience
to Bipolar Disorder, 2 years, $100,000
- James Boyer, Mount Desert Island Biologic Laboratory,
Development of a Comparative Toxicogenomics Database, 5 years, $22,890
- Michael Bracken, Johns Hopkins University, Genome-Wide
Association Studies of Asthma in Populations of African Descent, 3 years,
$188,881
- David Brissette, Physician Assistant Education Association,
Physician Assistants as Medicine Hospitalists, 1 year, $4,972
- Richard Bucala, Bay Pines Foundation, Release
of MIF Protein Complexes in Vivo: Response to Inflammation, 11
months, $13,272
- David Calderwood, U.S. Israel Binational Science Foundation,
Cytoplasmic Regulation of LFA-1 Assemblies Underlying Lymphocyte Adhesion
Transmigration and Immune Cell Recognition: The Talin Link, 4 years, $71,564
- Michael Carrithers, National Multiple Sclerosis Society,
T Lymphocyte Surveillance and the Neuroprotective Barriers in Health and
Disease, 3 years, $415,719
- Owen Chan, Juvenile Diabetes Research Foundation International,
Role of GABA in Modulation of Counterregulatory Responses to Hypoglycemia,
3 years, $89,308
- Junjie Chen, Susan G. Komen Breast Cancer Foundation,
Understanding the Tumor Suppression Function of BRCA1, 1 year, 7 months,
$120,080; Mayo Clinic of Rochester, Mayo Clinic Breast Cancer SPORE,
1 year, $178,326
- Paul Cleary, Harvard University, National Implementation
of Medicines Consumer Assessment of Healthcare Providers and Systems, 7
months, $117,978
- Michael DiGiovanna, Breast Cancer Research Foundation,
Activated HER2 as a Predictor of Therapeutic Response and as a Target in
Novel Combination Therapies, 1 year, $249,263
- Wawrzyniec Dobrucki, Juvenile Diabetes Research Foundation
International, Noninvasive Assessments of Myocardial and Peripheral Therapeutic
Angiogenesis in Animal Models of Type-1 Diabetes Mellitus, 3 years, $88,214
- Glen Farr, American Cancer Society, Regulation
of Na,K-ATPase Function by the Tetraspanin Protein CD81, 3 years, $138,000
- Simmie Foster, United Negro College Fund, An Adaptive
Response of the Innate Immune System, 2 years, $52,000
- Gerald Friedland, AIDS Project Hartford, HIV Prevention
Intervention Research with HIV positive Incarcerated Populations, 2 years,
$123,048
- Alison Galvani, James S. McDonnell Foundation, Developing
and Applying Game Theoretic Vaccination Models with Psychological Data,
6 years, $442,905
- Alexandria Garino, Physician Assistant Education Association,
Improving Clinical Anatomy Recall and Spatial Reasoning in Physician Assistant
Students,1 year, $2,500
- Walter Gilliam, Child Health & Development Institute
of Connecticut, Preschool Mental Health Climate Scale: A Tool for Preschool
Mental Health Consultants and Other Professionals, 1 year, $50,000
- Bryan Hains, Dana Foundation, Neuroimmune Modulation
of Chronic Pain after Spinal Cord Injury, 2 years, $200,000
- Robert Heimer, Gilead Foundation, Evaluating the
Effects of Expanded Hours for Syringe Exchange Programs in Connecticut,
1 year, $25,000; Gilead Foundation, Pilot Intervention Research: Brief Care-Based
HIV Prevention for Newly Diagnosed Men,1 year, $25,000
- Erica Herzog, Edward Mallinckrodt, Jr. Foundation,
Mechanisms of Bone Marrow: Epithelial Fusion in the Murine Lung, 3
years, $210,000
- Amy Justice, University of California, San Francisco,
Treatments for Complex Patients in New Settings, 1 year, $24,800
- Mark Mamula, L2 Diagnostics, LLC, Modified HER-2
Tumor Antigens for Vaccination in Cancer, 11 months, $264,075
- Aaron McGee, Burroughs Wellcome Fund, Inhibition
of Plasticity in the Adult Central Nervous System by Nogo-66 Receptor Signaling,
5 years, $500,000
- Haiying Meng, International Dyslexia Association,
A Deletion in Intron 2 of DCDC2 Gene Regulates Protein Expression in Developmental
Dyslexics, 1 year, $10,000
- Yorgo Modis, L2 Diagnostics, LLC, Broad Spectrum
Therapeutic Human Antibodies for Dengue Virus Infections, 1 year, $77,122;
L2 Diagnostics, LLC, Antivirals Targeting Flavivirus Envelope Proteins,
1 year, $153,384
- Kitt Petersen, Novartis Pharmaceuticals, Regulation
of Muscle PDH Flux in Different Populations, 9 months, $202,010
- Marc Potenza, University of Maryland at Baltimore,
Genetic Contributions to Adolescent HIV Risk Behavior, 1 year, $28,655
- Joseph Santos-Sacchi, Stanford University, New
Technologies for Investigation of the Hair Cell Afferent Fiber Synapse,
1 year, $74,587
- Gerald Shadel, American Federation for Aging Research,
Mouse Models of Aging and Age-Related Pathology via Mitochondrial DNA Transformation,
1 year, $124,296
- Wei-Xing Shi, National Alliance for Research on Schizophrenia
and Depression, Prefrontal Control of DA Neurons in the VTA, 2 years,
$100,000
- Gerald Shulman, Medical College of Georgia, Coordinating
and Bioinformatics Unit for the Mouse Metabolic Phenotyping Center, 5 years,
$511,500
- William Sledge, Eli Lilly and Company, Recovery
Guide Treatment Program for Recurrent Psychiatric Hospitalization, 1 year,
$99,193
- Stefan Somlo, Plexxikon, Graft Inhibitors in Polycystic
Kidney Disease, 1.5 years, $89,542; Icagen, Icagen Research Agreement,
1 year, $41,214
- Scott Strobel, Howard Hughes Medical Institute, Bioprospecting
for Natural Products in the World’s Rainforests: An Undergraduate Science
Expedition, 4 years, $1,000,000
- Fattaneh Tavassoli, Calibrant Biosystems, Breast
Cancer Proteome via Laser-Free Microdissection and Gemini Technologies,
2 years, $37,196
- Terence Trow, CoTherix, Educational Grant Agreement,
1 year, $5,000
- Ping Wang, American Heart Association (Heritage Affiliate),
Role of PLC-beta3 in the Initiation and Progression of Atherosclerosis,
1.5 years, $70,000
- Dianqing Wu, University of Connecticut, Vascular
Remodeling: Macrophage/Monocyte Signaling in Vascular Pathophysiology,
8 months, $148,873; University of Connecticut, Polarity in Networks and
Pathways: The Study of Neutrophil Polarity, 7 months, $70,307
- Zhinan Yin, Amino UP Chemical, AHCC Reduces Chemotherapy
Side Effects, 1 year, $19,800
- Yufeng Zhou, U.S. Israel Binational Science Foundation,
Activation Gating of Potassium Channel Pores: A Unifying Mechanism Controlled
by Hydrophobic Interactions, 4 years, $19,205
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