Medicine@Yale publication

July/August 2007   Volume 3 Issue 4

YSM Home Page | Medicine@Yale

Inside this issue

Cover stories

Passing the torch

Acquisition of Bayer site will accelerate biomedical research

International effort rewrites the book on the human genome

Partnerships

Foundation supports Yale research “of practical benefit”

Grants & contracts

People

Lifelines: Lawrence Cohen

Yale scientist is new president of Wellesley College

Top heart surgeon is named Glenn Professor

Diabetes experts win top scientific honors

Obstetrics/gynecology chair is honored as leader and writer

Out & about

Awards & honors

Science

Finding a new chink in cancer's armor

Research center aims to make rickets history

Brewing a new treatment for kidney disease

Advances: Putting a squeeze on Lyme disease | These mice like to spend time chilling | Hearing voices: A brain out of sync? | Stem cells show promise in Parkinson's

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Grants and contracts awarded to Yale School of Medicine

November/December 2006

Federal

• Walter Boron, NIH, Physiology of Electrogenetic Na/HCO₃ Cotransporters, 5 years, $1,900,958
  
• Junjie Chen, NIH, Study the Role of Chfr in Tumorigenesis, 4.5 years, $1,427,343
  
• Wonsun Han, NIH, Regulation of Na,K-ATPase Distribution and Function by Arrestin and Spinophilin, 2 years, $94,772
  
• Jonathan Kagan, NIH, Cellular and Molecular Aspects of Toll-Like Receptor Signal Transduction, 1 year, $89,996
  
• Chun Geun Lee, NIH, Genetic Factors Controlling Effector Function of TGF-Beta in COPD and Fibrosis, 5 years, $2,066,770
  
• Daeyeol Lee, NIH, Dynamics of Cortical Communication, 1.5 years, $262,321
  
• Michael Nitabach, NIH, Calcium Signaling in Circadian Clock Neurons, 4 months, $386,500
  
• Harvey Risch, NIH, Case-Control Study of Pancreas Cancer in Shanghai, China, 5 years, $3,596,491
  
• Bing Su, NIH, Regulation and Function of MEKK3 in Dendritic Cells, 1 year, $349,191; NIH, Molecular Mechanisms of MEKK3, 1.5 years, $143,759
  
• Patrick Sung, NIH, Molecular Basis of BRCA2-Mediated DNA Repair and Cancer Avoidance, 5 years, $1,841,689
  
• Terrence Town, NIH, Blocking TGF-Beta Immune Signaling as a Therapeutic Target for Alzheimer’s Disease, 1 year, $90,000
  
• Anthony Van den Pol, NIH, Hypocretin Neurons, 4 years, $1,447,487

Non-Federal

• Zane Andrews, Foundation for Research Science & Technology, Molecular and Neuroanatomical Mechanisms of Ghrelin Signaling in the Brain: Implications for Obesity, 1 year, $58,464
  
• Aydin Arici, Serono, Inc. (U.S.A.), The Role of AKT Signaling Pathway in the Pathogenesis of Endometriosis, 2 years, $56,824
  
• Xueying Chen, American Heart Assoc. (Heritage Affiliate), Computational Screening for Dosage-Sensitive Genes Involved in Cardiovascular Diseases, 1 year, $18,334
  
• Robert Constable, Pfizer, Inc., A Study to Investigate the Utility of Magnetic Resonance Endpoints for Defining Liver Disease in Subjects with Chronic HCV, 1 year, $195,568
  
• Karen Dorsey, St. Luke’s-Roosevelt Institute for Health Sciences, Metabolic Effects of Differential Organ Growth Rates, 6 months, $151,411
  
• Marie Egan, Cystic Fibrosis Foundation, Cystic Fibrosis Clinical Research Facilitation Awards, 1 year, $64,800
  
• Gerald Friedland, Institute for Clinical Research Inc., International Network for Strategic Initiatives in Global HIV Trials, 4.5 years, $513,621
  
• Bryan Hains, American Pain Society, Supraspinal Modulation of Pain after SCI by Microglia, 1 year, $20,000
  
• Kevan Herold, Juvenile Diabetes Research Foundation Int’l, Phase II Trial of hOKT3yl, 1 year, $82,537
  
• Fenghua Hu, Paralyzed Veterans of America, Mechanisms of Amino-Nogo Inhibition, 2 years, $100,000
  
• Henry Huang, GlaxoSmithKline Research & Development, Ltd., Evaluation of the PET Ligands [¹¹C]GSK81352 and [¹¹C]PHNO to Image Dopamine D3 Receptor in Rhesus Monkey, 9 months, $210,495; GlaxoSmithKline Research & Development, Ltd., Development of [¹¹C]/[¹⁸F]AFM for First-in-Human Trial of the Serotonin Transporter Ligand AFM, 1 year, $50,000
  
• Ivana Kawikova, Nat’l Alliance for Autism Research, Is Autoimmunity Involved in Pathogenesis of Autism? 2 years, $120,000
  
• John Krystal, Nat’l Alliance for Research on Schizophrenia and Depression, GABRA2 Modulation of NMDA Receptor Deficit-Related PFC Dysfunction, 1 year, $100,000
  
• Daeyeol Lee, University of Rochester, Neural Interactions Among Multiple Motor Structures, 3.5 years, $922,312
  
• Aliza Leiser, Ovarian Cancer Research Fund, Inc. (The), Clinical Implications of the TLR-4/MYD88 Pathway in Epithelial Ovarian Cancer, 2 years, $75,000
  
• Yorgo Modis, Roche Organ Transplantation Foundation, The Structural Basis of Innate Immune Sensing and Signaling by Toll-Like Receptors, 3 years, $242,484
  
• Mary Schwab-Stone, Leon Lowenstein Foundation, Inc., Greenwich Needs Assessment, 1 year, $25,000
  
• Patrick Sung, Lawrence Berkeley Nat’l Laboratories, Modulation of the Functionality of Homologous Recombinational Repair, 9 months, $120,649
  
• James Tsai, Synabridge Corporation, Instrument for Glaucoma Early Detection and Monitoring, 1.5 years, $102,881
  
• Carol Weitzman, Robert Wood Johnson Foundation, Identifying and Treating Maternal Depression in Underserved, Minority Women in a Pediatric Primary Care Setting, 2 years, $202,976
  
• Sandra Wolin, Ellison Medical Foundation, Investigating the Role of Oxidative RNA Damage in Aging, 4 years, $991,688
  
• Yong Xiong, Richard & Susan Smith Family Foundation, Mechanisms of HIV Suppression by Human Antiviral Protein APOBEC3 and HIV’s Countermeasures, 2 years, $200,000